Rejniak Lab News

*2018 September 25-28th, Annual Meeting of the PSON ndetwork and the CSBC network, Bethesda, MD

*2018 September 1st, Ms. Noemi Vitos has joined our lab as a visiting scholar.

*2018 August 6-9th, SIAM-LS bi-annual meeting, Minneapolis, MN; an invited talk presented by Kasia Rejniak.

*2018 July 27th, Final presentations of the HIP-IMO program. Shannon Chen and Shreya Mathur presented the results of their 8-week research project with our group.

*2018 July 23rd, Moffitt MRI Signalis has published a Spotlight interview with Kasia Rejniak.

* 2018 June 11th, Cancer Biology & Evolution Symposium, Moffitt, Tampa, FL. Talk given by Kasia Rejniak.

* 2018 June 4th-July 27th, Annual High School Summer Program HIP-IMO. Our group will host two high school students.

* 2018 May 29-31st, IMA Workshop for Women in Mathematical Biology, Minneapolis, MN. Talk given by Kasia Rejniak.

* 2018 May 22-25th, Conference on Cancer Evolution and Ecology: Theory and Clinical Practice, St. Pete Beach, FL. Talk given by Kasia Rejniak, and poster presented by Aleksandra Karolak.

* 2018 May 20th, our research on micro-pharmacology has been featured in The Medicine Maker.

* 2018 May 9th, Moffitt Cancer Center Scientific Symposium, Tampa, FL. Poster presentations by Aleksandra Karolak and Sharanm Poonja.

* 2018 April 30th, Moffitt Junior Researchers Scientiffic Retreat, Tampa.

* 2018 April 16-18th, UK Conference on Multiscale Biology at the University of Nottingham, UK, a plenary talk was given by Kasia Rejniak.

* 2018 April 14-18th, AACR Annual Meeting, a poster presentation Alan Roberts in collaboration with researchers form USF.

* 2018 March 16th, a Moffitt-funded Team Science Grant "Modulating the tumor microenvironment to improve immunotherapy in melanoma" with Dr. Shari Pilon-Thomas and Dr. Robert Gillies has been awarded!

* 2018 March 14th, our resent publications have been features in two issues of the Moffitt MRI Signals Newsletter.

* 2018 March 13th, our paper of targeted therapy micropharmacology has been feartured on Moffitt in The News website.

* 2018 March 5th, final presentations of Dartmouth College students spending a semester at an off-campus program at Moffitt-IMO.

* 2018 February 26th, our new paper "Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling" with Aleksandra Karolak and David Morse lab has been published by the Scientific Reports journal.

* 2018 February 23th, our new encyclopedia chapter "Single-Cell-Based In Silico Models: A Tool for Dissecting Tumor Heterogeneity" with Aleksandra Karolak, Saharsh Agrawal and Sam Lee has been published in Encyclopedia of Biomedical Sciences.

* 2018 February 23rd, USF Health Research Day, poster presentation given by Alan Roberts in collaboration with Dr. M. Wiranowska amnd Dr. N. Alcantar from USF.

* 2018 February 16th, Mr. Rupin Singh was awarded the second prize for our poster "Optimization of Nano-Drug Delivery to Ovarian Carcinoma and Glioma Cells" presented at the NanoBio Collaborative International Conference,Tampa, FL.

* 2018 February 13th, our new paper "Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling" with Aleksandra Karolak and David Morse lab has been accepted by the Scientific Reports journal.

* 2018 February 8th, Ms. Jessica Kingsley from University of South Florida have joined our lab as an undergraduate student intern.

* 2018 February 8th, our new paper "Micropharmacology: An In Silico Approach for Assessing Drug Efficacy Within a Tumor Tissue" with Aleksandra Karolak has been published by the Bulletin of Mathematical Biology.

* 2018 February 7-8th, our poster "Computational screening and quantitative modeling of the library of breast tumor spheroids under various microenvironments and treatments" was presented by Aleksandra Karolak at the "The Cancer Genomics and Mathematical Data Analysis Symposium" at Columbia University in New York.

* 2018 January 31st, a scientific Hat-Trick! Three publications in one month: (1) review in the Royal Society Interface; (2) chapter in the Tumor Organoids book; (3) paper in the Bulletin of Mathematical Biology.

* 2018 January 30th, our new paper "Micro-Pharmacology: An In Silico Approach for Assessing Drug Efficacy Within a Tumor Tissue" with Aleksandra Karolak has been accepted by the Bulletin of Mathematical Biology.

* 2018 January 24th, our new review paper "Toward Personalized Computational Oncology: from Spatial Models of Tumor Spheroids, to Organoids, to Tissues" with Aleksandra Karolak, Lisa McCawley and Dmitry Markov has been published by the Journal of The Royal Society Interface.

* 2018 January 19-20th, poster "Optimization of Nano-Drug Delivery to Ovarian Carcinoma and Glioma Cells" in collaboration with M. Wiranowska and N. Alcantar from USF has been presented by Mr. Rupin Singh at the NanoBio Collaborative Conference,Tampa, FL.

* 2018 January 16th, Mr. Sharan Poonja from University of South Florida have joined our lab as an undergraduate student intern.

* 2018 January 16th, IMO Research-in-progress seminar: current research results presented by Aleksandra Karolak.

* 2018 January 14th, a new book "Tumor Organoids" that includes a chapter from Aleksandra Karolak and Katarzytna Rejniak has been published by Springer.

* 2018 January 10th, Ms. Catherine Berrouet from Florida Atlantic University have joined our lab as a graduate student intern.

* 2018 January 2nd, our new review paper "Toward Personalized Computational Oncology: from Spatial Models of Tumor Spheroids, to Organoids, to Tissues" with Aleksandra Karolak, Lisa McCawley and Dmitry Markov has been accepted by the Journal of The Royal Society Interface.

Past news: 2017 ~~ 2016 ~~ 2015 ~~ 2014 ~~ 2013 ~~ 2012 ~~ 2011 ~~ 2010 News

 

 

2018 September 25-28th, CSBC & PSON Joint Annual Meeting, NIH, Bethesda, MD

A poster “In silico tumor organoids: delineation of microenvironmental and drug effects" has been presented by Kasia Rejniak and Dmitry Markov, and a lightning talk has been given by Lisa McCawley at the jopint meeting of the Cancer Systems Biology Network (CSBN) and the Physiocal Sciences Oncology Network (PSON).

 

2018 September 1st, Ms. Noemi Vitos from Sahlgrenska Academy, University of Gothenburg joined our lab as a visiting scholar.

 

2018 August 6-9th, a Bi-Annual Meeting of the Sociaty of Industrial and Aapplied Mathematics-Life Sciences (SIAM-LS) section, Minneapolis, MN, USA

An invited talk “Ductal Microinvasiona: Integrating Histology, Mechanobiology and Computational Modeling" has been given by Kasia Rejniak as a part of the minisymposium: Multi-ascale modeling of cell motility in cancer.

Kasia Rejniak has also chaired a plenary session and introduced the plenary speaker, Dr. Benjamin Ribba, Roche.

 

July 27th 2018, HIP-IMO Final presentations

Shannon Chen and Shreya Mathur presented: "Optimal schedules of combination therapies with hypoxia-activated pro-drug, the sensitizer and vasodilator in pancreatic cancer". Great job, Shreya and Shannon!

 

July 23rd 2018, Moffitt MRI Signals--Spotlight interview with Kasia Rejniak [interview]

 

2018 June 4th, Ms. Shreya Mathur and Ms. Shannon Chen joined our lab as summer high school student interns participating in the High School Internship Program HIP @IMO.

 

2018 May 29-31st, IMA Workshop for Women in Mathematical Biology, Minneapolis, MN.

A talk "Embracing complexity of the tumor microenvironment for personalized medicine" given by Kasia Rejniak in collaboration with Drs. D. Morse, R. Gillies, M. Bui and D. Reed.

 

 

2018 May 22-25th, Conference on Cancer Evolution and Ecology: Theory and Clinical Practice, St. Pete Beach, FL.

A talk "Drug-induced resistance: spatio-temporal lineage tree analysis" given by Kasia Rejniak, and a poster "Computational predictions of morpho-phenotypic features of tumor organoids under various microenvironments and treatments" presented by Aleksandra Karolak.

2018

 

2018 May, our research on micro-pharmacology has been featured in The Medicine Maker journal (p. 14-15) in an interview given by Kasia Rejniak and Aleksandra Karolak.

Interview: Staying on target.

 

May 9th 2018 -- Moffitt Cancer Center Scientific Symposium

Aleksandra Karolak presented a poster "Computational predictions of morpho-phenotypic features of tumor organoids under various microenvironments and treatments" in collaboration with Dr. McCawley and Dr. Markov from Vanderbilt University.

Sharan Poonja presented a poster "Reconstructing tumor growth in various microenvironments with the Organoid3D in silico model" in collaboration with Dr. McCawley and Dr. Markov from Vanderbilt University.

 

2018 April 16-18th UK Conference on Multiscale Biology, University of Nottingham, UK

An invited plenary talk “Up close and personal with chemotherapy: embracing the complexity of the tumor microenvironment” was given by Kasia Rejniak at the UK Conference on Multiscale Biology, hosted by the Centre for Mathematical Medicine and Biology (CMMB) at the University of Nottingham, UK

 

2018 April 14-18th, an Annual Meeting of the American Association of Cancer Research, Chicago, USA

A poster presentation "Quantitative Assessment of the Intracellular Uptake of Chlorotoxin in a U87 Human Glioma Mouse Model for the Targeted Drug Delivery System" by Mr. Alan Roberts in collaboration with Dr. M. Wiranowska and Dr. N. Alcantar from USF.

 

2018 March 16th, a Moffitt-Funded Team Science Grant "Modulating the tumor microenvironment to improve immunotherapy in melanoma" with Dr. Shari Pilon-Thomas and Dr. Robert Gillies has been awarded!

 

2018 March 14th, our resent publications have been featured in two issues of the Moffitt MRI Signals Newsletter: 01/31 issue: Interface paper & 03/14 issue: Scientific Reports paper.

 

2018 March 13th, our new paper "Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling" with Aleksandra Karolak and David Morse lab has been featured on Moffitt In The News website!

 

2018 March 5th, final presentations of Dartmouth College students spending a semester at an off-campus program at Moffitt-IMO. Lawrence Abu-Hammour working under the guidance of Aleksandra Karolak presented a talk "Image-based modeling of targeting nanoparticle delivery for high uniform receptor saturation". Great job, Lawrence!

 

2018 February 26th, our new paper "Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling" with Aleksandra Karolak and David Morse lab has been published by the Scientific Reports journal. link to the paper

 

2018 February 23th, our new encyclopedia chapter "Single-Cell-Based In Silico Models: A Tool for Dissecting Tumor Heterogeneity" with Aleksandra Karolak and two former HIP-IMO students Sam Lee and Saharsh Agrawal has been published in Encyclopedia of Biomedical Engineering, Elsevier. link to the publication

 

2018 February 23th, University of South Florida Health Research Day

A research poster "Quantitative Assessment of the Intracellular Uptake of Chlorotoxin in a U87 Human Glioma Mouse Model for the Targeted Drug Delivery System" presented by Mr. Alan Roberts in collaboration with Dr. M. Wiranowska and Dr. N. Alcantar from USF at the 2018 USF Health Research Day, Tampa, FL. USF e-poster

 

 

2018 February 8th, Ms. Jessica Kingsley from University of South Florida joins our lab as an undergraduate student intern to work on a research project "Mathematical Modeling of Microscale Pharmacology"

 

2018 February 8th, our new paper "Micropharmacology: An In Silico Approach for Assessing Drug Efficacy Within a Tumor Tissue" with Aleksandra Karolak has been published by the Bulletin of Mathematical Biology in the special issue "Mathematics to Support Drug Discovery and Development". link to the paper; link to article viewer

 

 

2018 January 31st, A real scientific hat-trick!

Three publications in one month: (1) Royal Society Interface review published online; (2) Tumor Organoids chapter published in print; (3) Bulletin of Mathematical Biology paper accepted. All three in collaboration with Aleksandra Karolak. Congratulations!

 

2018 January 24th, our new review paper "Toward Personalized Computational Oncology: from Spatial Models of Tumor Spheroids, to Organoids, to Tissues" with Aleksandra Karolak (Moffitt), Lisa McCawley (Vanderbilt) and Dmitry Markov (Vanderbilt) has been published by the Journal of The Royal Society Interface; link to the paper

 

2018 January 16th, Mr. Sharan Poonja from University of South Florida joins our lab as an undergraduate student intern to work on a research project "Histology-based Analysis and Modeling of Ductal Microinvasions"

 

2018 January 16th, IMO Research-in-Progress weekely seminar; Aleksandra Karolak has presented her work: "Computational screening and quantitative modeling of the library of breast tumor spheroids under various microenvironments and treatments" in collaboration with Lisa McCawley and Dmirty Markov labs at Vanderbilt

 

2018 January, a book "Tumor Organoids" edited by Shay Soker and Aleksander Skardal has been published by Springer Cancer Drug Discovery and Development Series. A contributed chapter "Mathematical Modeling of Tumor Organoids: Towards Personalized Medicine" by Aleksandra Karolak and Katarzyna Rejniak is included in this book. Link to the chapter.

 

2018 January 10th, Ms. Catherine Berrouet from Florida Atlantic University (FAU) joins our lab as a graduate student interns to continue a research project "Modeling 3D Tumor Response to Drugs based on IC50 Curves"