Past news: 2018 -- 2017 ~~ 2016 ~~ 2015 ~~ 2014 ~~ 2013 ~~ 2012 ~~ 2011 ~~ 2010 News

 

 

2019 December 5th, our new review paper "Hybrid modeling frameworks of tumor development and treatment" with Ibrahim Chamseddine has been published by WIREs Systems Biology and Medicinein the first 2020 issue: 12(1):e1461; link to publication

 

December 3rd 2019, IMO Research-in-Progress weekly seminar: Ibrahim Chamseddine has presented his work: "Vaccine-Induced Immunotherapy in Melanoma: Modeling and Schedule Optimization" in collaboration with Shari Pilon-Thomas lab.

 

2019 December 2nd, Mr. Szabolc Suveges from University of Dundee is visiting our lab to work on a joint hybrid modeling framework of tumor-ECM interactions.

 

	October 16-19th 2019, Biomedical Engineering Society Annual Meeting, Philadelphia
a poster "Optimizing the uptake of targeted therapies in an in silico model of pancreatic tumors" presented by Ibrahim Chamseddine.

 

2019 October 14th, Cancer Biology and Evolution Annual Symposium, Moffitt Cancer Center

Ibrahim Chamseddine has presened a lightning talk and a poster "Optimizing the uptake of targeted therapies in an in silico model of pancreatic tumor". Jessica Kingsley and Shreya Mathur have presented a poster "Medical imaging-based in silico reconstruction of tumor microenvironment" showing joint results with Sharan Poonja, in collaboration with Natarajan Raghunand (Cancer Physiology) and Marilyn Bui (Microscopy).

 

2019 October 11th, Mr. Luis Sanjuan from University of South Florida has joined our lab as an intern participating in the project "Tumor-iommune interactions in 3D microenvironments".

 

2019 October 4th, the Moffitt Junior Scientist Research Partnership Award "Machine learning to identify successful tumor infiltrating lymphocyte expansion (TIL) in bladder cancer" was granted to Ibrahim Chamseddine (Rejniak lab), Ali Hajiran (Poch lab) and Brittany Bunch (Pilon-Thomas lab). Congrats!!!!

 

	2019 September 18-20th, PSON Annual Meeting of Investigators, Minneapolis, MN
Ibrahim has presented a lightning talk and a poster titled: "Deconvolution of microenvironmental and drug effects on tumor growth using in silico organoids"; Kasia has presented a talk "Spatio-temporal changes in tumor and ECM architecture during early ductal invasions". Ibrahim won the People's Choice Award for his poster!!

 

2019 September 4th, our "Micropharmacology" paper with Aleksandra Karolak is finally in a printed volume of the Bulletin of Mathematical Biology, special issue on "Mathematics to Support Drug Discovery and Development". link to the paper; link to article viewer

 

	2019 August 22-23rd,CSBC-PSON Junior Investigators Meeting, Bethesda, MA
Ibrahim has presented a lightning talk and a poster titled: "Deconvolution of microenvironmental and drug effects on tumor growth using in silico organoids" summartizing the work related to our PSOP project with Vanderbilt University and performed by Aleksandra, Sharan, Jessica, Shreya and Ibrahim.

 

 

2019 August 21st, our new pre-print "Modeling vaccine-induced immunotherapy" with HIP-IMO students Priya Bhatt and Manoj Kambara, and with contribution form Shari-Pilon Thomas and Ibrahim Chamseddine has been published on BioRxiv. link to abstract.

 

2019 August, our review paper on hybrid modeling of tumor treastment was featured in Advanced Science News. Blog: Hybrid Modeling to Address Cancer Complexity.

 

	August 2nd 2019, Moffitt-IMO Research Day for the High School Intership Program (HIP-IMO), Tampa FL
a podium talk "Modeling Vaccine-Induced Immunotherapy. I: Optimizing Treatment Dosage and Timing; II: Studying Treatment Robustness Using Virtual Populations" was given by Priya Bhatt and Manoj Kambara to summarize the research project undertaken in collaboration with Dr. Shari Pilon-Thomas lab.

 

 

	August 1st 2019, Moffitt Research Day for the Summer Undergraduate Program to Advance Research Knowledge (SPARK), Tampa FL
a podium talk "Exploring the interplay between hypoxia, INF-gamma and CTL migration in the context of adoptive cell therapy" was given by Tamas Kis to summarize the research project undertaken in collaboration with Dr. Shari Pilon-Thomas lab.

 

	July 21-26th 2019, Society of Matematical Biology Annual Meeting, Montreal, Canada
a minisymposium "Advances in cancer treatment scheduling and optimization" organized by Ibrahim Chamseddine and Kasia Rejniak, and a podium talk "Optimising ligand propeerties in pancreatic cancer targeted therapy" presented by Ibrahim Chamseddine.

 

	July 15-19th 2019, International Congress on Industrial and Applied Mathematics, Valencia, Spain
a podium talk "Up close and personal with chemotherapy: embracing complexity of the tumor microenvironment" presented by Kasia Rejniak.

 

2019 July 3rd, an NIH-PSON-funded Supplement Grant "Macrophage-mediated breast tumor response to ER inhibitors in 3D Microenvironments" in collaboration with Dr. Brian Ruffell has been awarded!

 

July 2nd 2019, HIP-IMO Research in Progress presentations

Priya Bhatt and Manoj Kambara presented their research project "Modeling Vaccine-Induced Immunotherapy" and the research topics on optimizing T cell-based treatment and studying treatment ronbustness. Great job, Pryia and Manoj!

 

2019 June 27th, our new research paper "Morphophenotypic classification of tumor organoids as an indicator of drug exposure and penetration potential" with Aleksandra Karolak and Sharan Poonja has been accepted by PLoS Computational Biology; link to publication

 

2019 June 16-21st, Bridging Cellular and Tissue Dynamics from Normal Development to Cancer: Mathematical, Computational, and Experimental Approaches, BIRS, Banff, Canada

Kasia presented a talk "Ductal Microinvasions: Cell and Matrix Interactions in Normal and Cancerous Tissues" in collaboration with Saharan Poonja, Jessica Kingsley, Aleksandra Karolak and Moffitt Microscopy Core. link to the talk

 

2019 June 13th, our new review paper "Hybrid modeling frameworks of tumor development and treatment" with Ibrahim Chamseddine has been accepted by WIREs Systems Biology and Medicine; link to publication

2019 June 10th, Ms. Priya Bhatt and Mr. Manoj Kambara have joined our lab as summer high school student interns participating in the High School Internship Program HIP @IMO.

 

2019 June 4th, Ms. Shreya Mathur joined our lab as a returning summer intern. She was a HIP participant last year. She will continue working on a project "Optimal schedules of combination therapies with hypoxia-activated pro-drug".

 

2019 May 21st, Mr. Tamas Kis joined our lab as a SPARK intern. He is an undergraduate student at the Vanderbilt University. He will work on a project "Metabolic reprogramming to improve immunotherapy in melanoma".

 

2019 May 19-24th, International Conference on Computational and Mathematical Population Dynamics, Fort Lauderdale Beach

Catherine Berrouet and Naika Dorillas presented a poster "A Mathematical Model of Anti-Cancer Drugs’ IC50 Values in Monolayer and Spheroid Cultures" in collaboration with Necibe Tuncer from Florida Atlantic University and Kasia.

 

 

2019 May 13th, Ms. Jessica Kingsley joined our lab as a research assistant. She is an undergraduate student at the University of South Florida. She will work on modeling of metabolic fluctuations in DCIS.

 

2019 May 13-14th, Mathematical Oncology Meeting at the Knight Cancer Research Center in Portland, OR

Ibrahim Chamseddine presented a poster "Novel Method for Optimizing Anti-Cancer Treatments: An Application to Pancreatic Tumors" in collaboration with former postdoc Aleksandra Karolak and HIP-IMO students Sherya Mathur and Shanon Chen Kasia Rejniak gave a talk "Hypoxia in cancer chemo- and immunotherapy: foe and friend?" in collaboration wit Noemi Vitos, Sherya Mathur, Shanon Chen and Ibrahim Chamseddine.

 

 

2019 May 7th, our new meeting abstract "Hypoxia in cancer chemo- and immunotherapy: foe or friend?" with Noemi Vitos, Shannon Chen, Shreya Mathur and Ibrahim Chamseddine has been published on BioRxiv. link to abstract.

 

2019 May 1-2nd -- Moffitt Cancer Center Scientific Symposium

Ibrahim Chamseddine presented a poster "Novel Method for Optimizing Anti-Cancer Treatments: An Application to Pancreatic Tumors" in collaboration with former postdoc Aleksandra Karolak and HIP-IMO students Sherya Mathur and Shanon Chen.

 

 

April 6-7th 2019, Association of Women in Mathematics (AWM) Reseaerch Symposium, Rice University, Houston, TX

a poster "A Mathematical Model of Anti-Cancer Drug’s IC50 Values in Monolayer and Spheroid Cultures" was presented by Catherine Berrouet from Florida Atlantic University; joint project in collaboration with Naika Dorilas and Necibe Tuncer (Florida Atlantic University) and Kasia Rejniak (Moffitt).

 

 

2019 March 14th, The Quantitative Science Division Celebration of the Pi Day ~~ 3.14.

 

2019 February 27th, the Florida Department of Health Bankhead-Coley Bridge Grant "Metabolic reprogramming to improve immunotherapy in melanoma" with Dr. Shari Pilon-Thomas and Dr. Robert Gillies has been awarded!

 

	February 10-15th 2019, Gordon Research Conference on Physical Science of Cancer, Galveston, TX
a poster "Tumor-matrix interactions in early ductal invasions: integrsting histology, mechanobiology and computational modleing" in collaboration with Jessica Kingsley, Sharan Poonja, Marilyn Bui, Agnieszka Kasprzak and Mark Lloyd was presented by Kasia Rejniak.

 

 

2019 February 5th, a patent "Pathology case review, abalyis and prediction" has been awarded to Kasia Rejniak in collaboration with Mark lloyd, Marilyn Bui and Munish Puri.

 

2019 February 5th, Faculty Appreciation and Recognition Ceremony & 10 year anniversary of Kasia Rejniak employment.

 

2019 January 14th, Dr. Ibrahim Chamseddine joined our lab as a postdoctoral fellow. Dr. Chamseddine received his PhD degree from the Engineering Department of the McGill University in Canada. He will work on modeling and optimization of treatment schedules.

 

2019 January 10th, a Moffitt-funded CIIRC Grant (the Center for Immunization and Infection Research in Cancer) "Optimizing vaccine-based immunotherapy using virtual treatment optimization software (VirTuOSo)" with Dr. Shari Pilon-Thomas has been awarded!