2025 August 1st, HIP-IMO Research Day with final students' presentations

After an 8 week-long research on scientific projects, the final presentations were given by Lamees, Bruce, and Luke. — Lamees discussed her project: "Investigating model parameter dynamics for MDSCs in combination therpy for bladder cancer using PINN" — Bruce discussed his project: "Investigating fibroblast impact on tumor mivroinvasions" — Luke discussed his project: "Testing NMIBC treatments with virtual cohorts".

 

2025 July 13-18th, Annual meeting of the Society for Mathematical Biology (SMB), Edmonton, Canada

Rejniak Lab team at the SMB25: Kasia, Hannah, Ana, and Jessica (former member), and Daniel (right picture, an honorary member)

Hannah organized a minisymposium "Advances in Optimal Control Methods for Diverse Modeling Frameworks" and presented a talk "Optimal control of adoptive T-cell therapy and gemcitabine in non-muscle invasive bladder cancer"; Ana presented a talk "An agent-based model with ECM to study the mechanics of DCIS microinvasions";

Kasia talked on "Data-based models for guiding adoptive cell immunotherapies in bladder cancer" and "Using tumor histology to analyze cancer immunotherapies with the agent-based micropharamacology model".

 

2024 July 9th, HIP-IMO midterm presentations

Lamees discussed her project "Investigating model parameter dynamics for MDSCs in combination therpy for bladder cancer using PINN", Bruce discussed his project "Investigating fibroblast impact on tumor mivroinvasions", Luke discussed his project "Testing NMIBC treatments with virtual cohorts".

 

2024 June 14th, HIP-IMO Journal Club Meeting

Lamees presented a paper on a physics-informed neural network approach, Bruce presented a paper on a 3D agent-based model of tumor organoids, Luke presented a paper on designing a virtual mouse cohort.

 

2025 June 9th, Ms. Lamees El Naqa, Mr. Bruce Williams, and Mr. Luke Stoughton have joined our lab as HIP-IMO program participants. Lamees will work under the mentorship of Kayode, Bruce will work under the mentorship of Ana, and Luke will work under the mentorship of Hannah.

 

2025 May 28th, a new paper from our lab: "Optimizing the Efficacy of Vaccine-Induced Immunotherapy in Melanomas" by Ibrahim Chamseddine and two prior HIP-IMO interns Manoj Kambara and Priya Bhatt, in collaboration with Shari Pilon-Thomas lab, and Kasia Rejniak, has been published in Bulletin of Mathematical Biology, link to the article

 

2025 May 12-13th, 15th Annual Moffitt Scientific Symposium, Moffitt.

Ana presented a poster: "In silico modeling of cell-stroma mechanical interactions in DCIS progression" and Hannah presented poster: "Developing a virtual cohort for adoptive cell therapy in bladder cancer". Grest discussions! Congratualtions to Hannah for winning a Quantitative Science Poster Award

 

2025 May 11-15th, Bi-annual meeting of the Society of Industrial and Applied Mathematics, Dynamical Systems group (SIAM-DS)

Podium talk "Modeling Adoptive Cell Therapy in Bladder Cancer Using Physics-Informed Neural Network with Biology Constraints" was presented by Kayode.

 

2025 March 18th, IMO Research in Progress seminar

Ana presented a summary of her PhD researech project: "Investigating tumor-stroma physicochemical interactions in DCIS microinvasions".

 

2025 March 14th, QuantSci Pi Day celebration.

Pi Day celebration by the Quantitative Sciences Division -- Rejniak Lab: Tyler, Kasia, Hannah, Kayode, Ana, and Emilie.

 

2025 January 26th, a new paper from Guevara lab with our contribution: "Effector T Cells under Hypoxia have an Altered Transcriptome Similar to Tumor-Stressed T Cells Found in Non-Responsive Melanoma Patients" has been published in Journal for ImmunoTherapy of Cancer. link to publication

 

2025 February 1-7th, Gordon Research Seminar and Conference on Physical Science of Cancer

Ana will present her work "In silico model of cell-stroma mechanical interactions in DCIS progression" in collaboration with Mehdi Damaghi lab at Stony Brook University

 

2025 January 8th, a new preprint from our lab: "Optimizing the Efficacy of Vaccine-Induced Immunotherapy in Melanomas" by Ibrahim Chamseddine and two prior HIP-IMO interns Manoj Kambara and Priya Bhatt, in collaboration with Shari Pilon-Thomas lab, and Kasia Rejniak, has been published in BioRxiv, link to the article